Tardive dyskinesia as a risk factor for negative symptoms
نویسندگان
چکیده
منابع مشابه
Risk Factors for Tardive Dyskinesia
Second-generation (atypical) antipsychotic agents are being used within their indications as well as widely off-label because of their lower risk of causing extrapyramidal symptoms and tardive dyskinesia (TD). The risk of metabolic disorders has taken over much of clinical practice and the current literature on adverse effects. In this brief article, we discuss a case of TD that developed after...
متن کاملRisk Factors for Tardive Dyskinesia
Three hundred and fifty three patients who had been on antipsychotics for three months or more were assessed using Simpson Tardive Dyskinesia Rating Scale. 40.2% of these patients, who merited a diagnosis of probable Tardive Dyskinesia (TD) by the Schooler and Kane criteria, were reassessed three months later and 25.5% of the total sample were found to have persistent TD. Age, total antipsychot...
متن کاملDehydroepiandrosterone sulphate as a putative protective factor against tardive dyskinesia
BACKGROUND Tardive dyskinesia (TD) is a potentially irreversible consequence of long term treatment with antipsychotic drugs which is according to a well-known theory believed to be related to oxidative stress induced neurotoxicity. Dehydroepiandrosterone (DHEA) is an endogenous antioxidant with neuroprotective activity. The biosynthesis of DHEA depends upon the activity of cytochrome P450c17α ...
متن کاملTardive dyskinesia and positive and negative symptoms of schizophrenia. A study using instrumental measures.
BACKGROUND Controversy surrounds the relationship between tardive dyskinesia (TD) and symptoms of schizophrenia. While some studies reported that negative symptoms of schizophrenia may be a risk factor for TD, others reported a relationship between TD and positive symptoms. METHOD Eighty-four patients were studied, of whom 47 met criteria for TD. Clinical and instrumental procedures were used...
متن کاملParkinsonian symptoms in tardive dyskinesia. A prevalence study.
Of 49 unselected patients with tardive dyskinesia (TD) 28 (57%) exhibited various parkinsonian signs. Isolated tremor was encountered in 11 patients, tremor with hypokinesia and rigidity in 13 patients, and hypokinesia and rigidity alone in 4. Tremor was detected among patients with scorable peripheral signs of TD. Hypokineto-rigidity, with or without tremor, was attributed to high doses of neu...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 1994
ISSN: 0007-1250,1472-1465
DOI: 10.1192/s0007125000034607